By Air 
Ft. Myers airport is convenient and only 45 minutes from the condo. After leaving the airport:

 Follow Daniel's towards I-75 and continue under the highway.
 Left onto Summerlin
 Follow through the toll booth onto Sanibel Island

Tampa airport is about 2-1/2 hours away but it is an easy drive. Take I-275 south to I-75 south and follow the directions below.

By Car  Take I-75 south to exit 21.  Turn right as you exit the highway onto Daniel's.  Left onto Summerlin  Follow through the toll booth onto Sanibel Island On the Island  After crossing the causeway, pick up the key from the rental office.  Turn right onto Periwinkle Way  Follow to the end and turn left on Tarpon Bay  Follow to the end and turn left of West Gulf Drive  Pointe Santo is the second & third driveway on the right